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titlelines Management of Arrhythmias in Patients with Ischemic Heart Disease

In this symposium, the current management of arrhythmias in patients with ischemic heart disease will be reviewed, with an emphasis on the benefit/risk to the patient, and unmet needs for development of new therapies.

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Program Overview

Pharmacologic and nonpharmacologic therapy both hold an important place in the management of cardiac arrhythmias.  For example, both strategies are recommended in atrial fibrillation guidelines.  Heart rate vs. rhythm control for patients with atrial fibrillation has indeed been intensely studied and debated, and choice of strategy depends on a number of factors.  Patients with ischemic heart disease and arrhythmias such as atrial fibrillation are one such patient population.  Management with drug therapy using agents such as dofetilide, sotalol, and amiodarone has been recommended, however with elaboration of potentially serious side effects.  Therefore, there is a clear need for drugs possessing greater efficacy and safety in these patients.  In this symposium, current management of arrhythmias in patients with ischemic heart disease will be reviewed, with emphasis on benefit/risk to the patient, and unmet needs for development of new therapies.  In addition, recent data with new pharmacologic approaches will be described, with discussion about their potential utility in patients with ischemic heart disease and different types of arrhythmia.

Educational Objectives

Upon completion of this program, attendees will be able to:

  • In patients with ischemic heart disease, describe the benefits and risks of current anti-arrhythmic agents, and identify unmet needs for new therapies.
  • Explain mechanistic strategies for intervention for potential anti-arrhythmic drugs

Target Audience

This program was developed for the education of electrophysiologists and other health care professionals involved in the treatment of patients with cardiac arrhythmias.

Faculty Information and Disclosures

Jeremy N. Ruskin, MD
Director, Cardiac Arrhythmia Service
Massachusetts General Hospital
Associate Professor of Medicine
Harvard Medical School
Boston, MA

Peter R. Kowey, MD
Professor of Medicine and Clinical Pharmacology
Jefferson Medical College
Philadelphia, PA

Disclosure Statement

It is the policy of Voxmedia to ensure the unbiased, fair-balanced and scientifically rigorous nature of all directly or jointly sponsored educational activities. All prospective faculty are required to disclose any significant financial or other interest or relationship (1) with the manufacturer(s) of any commercial product(s), device(s) or service(s) AND (2) with any commercial supporters of an activity prior to participating in the planning of an activity, contributing to content, or making a presentation. Only then will faculty receive approval to participate. Faculty are expected to contribute evidence-based materials and information.  Faculty are required to indicate areas of their presentation that are based onprofessional opinion vs. guidelines, meta-analysis etc. All information is peer-reviewed.

Faculty Disclosures

Peter R. Kowey, MD
Grants/Research Support: CV Therapeutics, Inc.
Consultant: CV Therapeutics, Inc.
Honorarium: CV Therapeutics, Inc.

Jeremy N. Ruskin., MD
Grants/Research Support: Guident Corporation, Medtronic, Inc., St. Jude Medical
Consultant: Astellas Pharma Inc., CV Therapeutics, Inc., Medtronic, Inc., Pfizer Inc., sanofi-aventis
Honorarium: Guident Corporation, St. Jude Medical

Program Agenda

Introduction
Jeremy N. Ruskin, MD - Chair

Management of Arrhythmias in Patients With Ischemic Heart Disease: Weighing the Benefits and Risks
Jeremy N. Ruskin, MD

New Approaches to Arrhythmia Management in Patients With Ischemic Heart Disease
Peter R. Kowey, MD

Accreditation Statement

Voxmedia LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Educational Grant

Voxmedia International gratefully acknowledges the educational grant provided by CV Therapeutics, Inc.

Target Audience

This program was developed for the education of electrophysiologists and other health care professionals involved in the treatment of patients with cardiac arrhythmias.

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Disclaimer Statement

This educational activity may include references to the use of products for indications not approved by the Food and Drug Administration (FDA). The drug selection and dosage information provided in this publication are believed to be accurate. However, readers are urged to check the package insert for each drug for recommended dosage, indications, contraindications, warnings, precautions, and adverse effects before prescribing any medications. This is particularly important when the drug is new or infrequently used.

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Management of Arrhythmias in Patients with Ischemic Heart Disease

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This activity has been supported by an educational grant from CV Therapeutics, Inc. This activity is sponsored by Voxmedia LLC. Voxmedia takes responsibility for the content, quality, and scientific integrity of this educational activity.

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Copyright

© 2008 Voxmedia International.  All rights reserved including translation into other languages.  No part of this publication may be reproduced or transmitted in any form or by any means- electronic or mechanical, including photocopying, recording, or any information storage and retrieval system- without permission in writing from Voxmedia.  Permission has been granted for the use of all materials used or adapted in this educational activity and will be indicated under each figure, table, or other item.

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