Dr. Charles Antzelevitch's contributions to scientific literature include more 375 papers and four books.
How long have you been a member of the Heart Rhythm Society?
Why did you choose the field of electrophysiology?
At the start of my career there was nothing more exciting than watching an action potential or electrocardiogram dance across the oscilloscope screen. As I progressed in my career, I became fascinated with the intricacies of mechanisms underlying arrhythmogenesis in a wide range of pathologies. With the advent of molecular genetics, electrophysiology took an exciting leap advancing our understanding of inherited cardiac arrhythmia syndromes, permitting us to better diagnose these syndromes and find novel approaches to therapy.
How has membership in the Society been of value to you and your practice?
The Heart Rhythm Society has played a key role in my development as a scientist, providing a forum to meet and learn from esteemed colleagues from every corner of the world and opening doors that have permitted me to mature as an investigator, educator and administrator.
Please list a few of your most recent accomplishments.
Scientific achievements include:
- The discovery and characterization of reflected reentry and phase 2 reentry as mechanisms of extrasystolic activity capable of precipitating life-threatening ventricular tachycardia and fibrillation
- Demonstration of electrical heterogeneity within ventricular myocardium, which has opened a new door to our understanding of electrophysiology and pharmacology of the heart and mechanisms of arrhythmogenesis
- Contribution to delineation of the cellular, ionic and genetic basis for the long QT, Brugada, and short QT syndromes as well as catecholaminergic VT
- The cellular, ionic and genetic factors that influence the J wave and T wave of the ECG.
More About Charles Antzelevitch, PhD, FHRS
Dr. Antzelevitch is the Executive Director and Director of Research of the Masonic Medical Research Laboratory (MMRL), an internationally prominent biomedical research institute located in Utica, NY. He also holds an academic appointment as Professor of Pharmacology at the Upstate Medical University in Syracuse and an endowed chair in Experimental Cardiology (Gordon K. Moe Scholar) at the MMRL. His contributions to the scientific literature include more than 375 papers and four books. He is an internationally recognized authority in cardiac electrophysiology and arrhythmias — inherited cardiac arrhythmias in particular. Recent awards include the Distinguished Scientist Award of the North American Society of Pacing and Electrophysiology (NASPE — now the Heart Rhythm Society), Excellence in Cardiovascular Science Award of the NE Affiliate American Heart Association and the Carl J. Wiggers Award of the American Physiological Society. From 1996 to 1998, he served as President of the International Cardiac Electrophysiology Society and currently serves as Secretary/Treasurer of the Society.