New Study Shows Hispanics And African Americans With Heart Failure Have Lower Risk Of Developing Atrial Fibrillation Compared To Whites

Presented at Heart Rhythm 2016, large study analyzes more than 68,000 patients and illustrates interaction between heart failure and atrial fibrillation in different races and ethnicities

May 04, 2016

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Allison Kassel
BRG Communications
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Shane Osborne
Heart Rhythm Society
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SAN FRANCISCO, May 4, 2016 – A new study presented today at Heart Rhythm 2016, the Heart Rhythm Society’s 37th Annual Scientific Sessions, found that among patients with heart failure, atrial fibrillation (AF) was significantly less common among African Americans and Hispanics than among non-Hispanic Whites. This study indicates a strong correlation between race and ethnicity and the development of AF for patients with heart failure.

Heart failure is a common risk factor for AF and is a major public health issue, with a prevalence of over 5.8 million in the U.S., over 23 million worldwide and rising. Specifically, heart failure is more prevalent in African Americans and Hispanics than in non-Hispanic Whites. The higher heart failure burden but lower prevalence of AF in African Americans compared to non-Hispanic Whites is known as the “racial paradox.” However, the contribution and interaction of heart failure for AF in Hispanic minorities is largely unknown.

The study analyzes a large population of 68,022 patients between the ages of 45 and 95. Patient data from 28,489 Hispanics, 25,204 African Americans and 14,329 non-Hispanic Whites was studied for the presence of AF, diagnosed using electrocardiograms (EKGs), and for the presence of heart failure, detected using diagnosis code ICD-9. Analysis was then performed to determine the independent predictive ability of heart failure by race and ethnicity to predict AF.

The prevalence of heart failure and AF varied by race and ethnicity. After adjusting for risk factors, the presence of heart failure in Hispanics and African Americans was associated with significantly lower odds of developing AF than in non-Hispanic Whites. Specifically, results show African Americans and Hispanics are 23.2 percent and 26.9 percent, respectively, less likely than non-Hispanic Whites to develop AF.

“Our analysis shows an independent association between race and ethnicity and atrial fibrillation in a large population with heart failure, which is something largely unknown, specifically within the Hispanic population. It’s especially interesting because, despite having many risk factors for AF, Hispanic and African American patients had a lower risk of developing AF,” said Eric H. Shulman, MD, Montefiore Medical Center, Bronx, NY. “There may be an underlying genetic reason for why we saw such significant differences between these groups. Better understanding and awareness of the disparities between heart failure and atrial fibrillation by race and ethnicity will help physicians develop a more individualized approach to patient care moving forward.”

The study authors note that further research is needed to understand the interrelations of heart failure and AF in racial and ethnic minorities in order to inform prevention strategies for both adverse conditions.

Sessions details:

“Atrial Fibrillation in Hispanics, Blacks and non-Hispanic Whites with Heart Failure” [Wednesday, May 4, 2016, 5:00 p.m. – 6:30 p.m. PDT, EPicenter, Hall D]

Heart Rhythm 2016 is the most comprehensive educational program for heart rhythm professionals, featuring more than 250 educational sessions and more than 130 exhibitors showcasing innovative products and services. The Heart Rhythm Society’s Annual Scientific Sessions have become the must-attend event of the year, allowing the exchange of new vital ideas and information among colleagues from every corner of the globe.

About the Heart Rhythm Society

The Heart Rhythm Society is the international leader in science, education and advocacy for cardiac arrhythmia professionals and patients, and the primary information resource on heart rhythm disorders. Its mission is to improve the care of patients by promoting research, education and optimal health care policies and standards. Incorporated in 1979 and based in Washington, DC, it has a membership of more than 5,900 heart rhythm professionals in more than 70 countries around the world. For more information, visit www.HRSonline.org .