The Late-Breaking Clinical Trials Sessions are always one of the most anticipated elements of the Society's Annual Scientific Sessions. Select authors present groundbreaking work; abstracts will appear in a future issue of HeartRhythm Journal.

The Heart Rhythm Society recognizes that due to the scheduling requirements, some exciting and rapidly evolving research could not be completed in time for the abstract submission deadline. In an effort to highlight timely and novel work at Heart Rhythm 2009, the Scientific Sessions Program Committee developed a peer-reviewed session of late-breaking trials that allows for later submission. A number of the below sessions are available for immediate viewing as a Heart Rhythm 2009 expedited webcast.

Late-Breaking Clinical Trials I
Thursday, May 14, 2009
10:30 a.m.–Noon
Ballroom West

Chairs:
Mark H. Schoenfeld, MD, FHRS, CCDS
Yale University School of Medicine
New Haven, CT

Dwight W. Reynolds, MD, FHRS
University of Oklahoma Health Sciences Center
Oklahoma City, OK

• Survival After ICD and CRT-D Implant in A Large Cohort of Heart Failure Patients Treated with Contemporary Drug and Device Therapies — Results of the ALTITUDE Study — 
  Leslie A. Saxon, MD, FHRS, CCDS
  USC Keck School of Medicine, Los Angeles, CA
       » Download ALTITUDE abstract (PDF, 30k)
• Long-Term Outcome after Implantation of a Cardioverter Defibrillator: An Eight Year Follow-Up Study of the Multicenter Automatic Defibrillator Trial II — 
  Ilan Goldenberg, MD
  Heart Research Follow-up Program, University of Rochester Medical Center, Rochester, NY
       » Download MADIT-II abstract (PDF, 111K)
• Recurrent Atrial Arrhythmias And Quality-Of-Life In Patients With Paroxysmal Atrial Fibrillation Treated By Radiofrequency Catheter Ablation Compared To Antiarrhythmic Drug Therapy: Final Results Of The Thermocool AF Trial — 
  David J. Wilber, MD
  Loyola University Medical Center, Maywood, IL
       » Download Thermocool AF abstract (PDF, 31K)
• Substrate vs Trigger Ablation for Reduction of Atrial Fibrillation (STAR-AF): An International, Multicenter, Randomized Trial — 
  Atul Verma, MD
  Southlake Regional Health Center, Newmarket, ON, Canada
       » Download STAR-AF abstract (PDF, 46K)
• Worldwide Randomized Clinical Trial to Evaluate New Pacemaker System Designed for Use During Magnetic Resonance Imaging — 
  Bruce L. Wilkoff, MD, FHRS, CCDS
  Cleveland Clinic, Cleveland, OH
       » Download new pacemaker system trial abstract (PDF, 31K)
• Complication rates associated with pacemaker and implantable defibrillator generator replacement: Results from the REPLACE Registry — 
  Marye J. Gleva, MD
  Washington University School of Medicine, Saint Louis, MO
       » Download REPLACE abstract (PDF, 18K)

Late-Breaking Clinical Trials II
Friday, May 15, 2009
8:00 – 9:30 a.m.
Ballroom East

Chair:
Stuart J. Connolly, MD
McMaster University
Hamilton, ON, Canada

• Atrial Support Pacing in Heart Failure: Results from the Multicenter PEGASUS CRT Trial — 
  David O. Martin, MD, MPH
  Cleveland Clinic Foundation, Cleveland, OH
       » Download PEGASUS abstract (PDF, 40K)
• Atrial Pacing or Ventricular Backup Pacing in Implantable Cardioverter-Defibrillator Patients: The Managed Ventricular Pacing versus VVI 40 Pacing (MVP) Trial — 
  Michael O. Sweeney, MD
  Brigham and Women's Hospital, Boston, MA
       » Download MVP abstract (PDF, 58K)
• PASCAL: A Randomized, Double-Blind, Placebo-Controlled Study of Budiodarone (ATI-2042) in Patients with Paroxysmal Atrial Fibrillation and Pacemakers with Atrial Fibrillation Data Logging Capabilities — 
  Michael D. Ezekowitz, MD, Ph.D.
  Lankenau Institute for Medical Research, Wynnewood, PA
       » Download PASCAL abstract (PDF, 60K)
• Effects of dronedarone on clinical outcomes in patients with atrial fibrillation and congestive heart failure: insights from ATHENA — 
  Stefan H. Hohnloser, MD, FHRS
  J. W. Goethe University, Frankfurt, Germany
       » Download ATHENA abstract (PDF, 28K)
• Percutaneous Left Atrial Appendage Closure versus Warfarin for Stroke Prevention in Atrial Fibrillation Patients (PROTECT AF): Results from CHADS2 1 & 2 Patients — 
  Vivek Y. Reddy, MD
  University of Miami, Miami, FL
       » Download PROTECT abstract (PDF, 119K)
• Clinical evaluation of the subcutaneous implantable defibrillator (S-ICD®) system — 
  Ian G. Crozier, MD
  Christchurch Hospital, Christchurch, New Zealand
       » Download S-ICD® abstract (PDF 25K)