Discussion Topic: Improved PAF Trial, Pulmonary Vein Isolation with and without Posterior Wall Isolation in Paroxysmal Atrial Fibrillation by Arash Aryana et al
Jason T. Jacobson, MD, FHRS, is joined by guests Laurent Macle, MD, FHRS, and Peter M. Kistler, MBBS, PhD, FHRS, for a discussion of the Improved PAF Trial. Prior studies have demonstrated clinical benefits associated with cryoballoon pulmonary vein isolation (PVI) and concomitant posterior wall isolation (PWI) in patients with persistent atrial fibrillation (AF). However, the role for this approach in patients with paroxysmal atrial fibrillation (PAF) remains unclear. Compared with cryoballoon PVI, cryoballoon PVI+PWI appears to be associated with greater freedom from recurrent atrial arrhythmias and AF in patients with PAF during long-term follow-up >3 years.
Host: Jason T. Jacobson, MD, FHRS
Guests: Peter M. Kistler, MBBS, PhD, FHRS and Laurent Macle, MD, FHRS
Speaker and Article Information: Download
Topic
- The Lead
Resource Type
- Podcasts
Related Resources

Podcasts
The Lead Episode 103: A Discussion of Independent External Evaluation of Pediatric Hypertrophic Cardiomyopathy Risk Scores... Live at HRS 2025 in San Diego
May 15, 2025

Podcasts
The Lead Episode 102: A Discussion of Repeat Procedures after Pulsed Field Ablation for Atrial Fibrillation, the MANIFEST-REDO Study
May 8, 2025

Podcasts
The Lead Episode 101: A Discussion of Pulsed Field or Cryoballoon Ablation for Paroxysmal Atrial Fibrillation
April 30, 2025