Discussion Topic: Long-Term Outcomes of Brugada Substrate Ablation: A Report from BRAVO
William H. Sauer, MD, FHRS, CCDS, of Brigham and Women’s Hospital, is joined by guests Michael G. Katz, MD, FHRS, of Morristown Medical Center and Victor Nauffal, MD, of Brigham and Women`s Hospital, to discuss the treatment options for high-risk Brugada syndrome (BrS) with recurrent ventricular fibrillation (VF) and how it is limited. Catheter ablation is increasingly performed, but a large study with long-term outcome data is lacking. We report the results of the multicenter, international BRAVO (Brugada Ablation of VF Substrate Ongoing Registry) for treatment of high-risk symptomatic BrS. Ablation treatment is safe and highly effective in preventing VF recurrence in high-risk BrS. Prospective studies are needed to determine whether it can be an alternative treatment to implantable cardioverter-defibrillator implantation for selected patients with BrS.
Host: William H. Sauer, MD, FHRS, CCDS
Guests: Michael G. Katz, MD, FHRS and Victor Nauffal, MD
Speaker and Article Information: Download
Topic
- The Lead
Resource Type
- Podcasts
Related Resources

Podcasts
The Lead Episode 101: A Discussion of Pulsed Field or Cryoballoon Ablation for Paroxysmal Atrial Fibrillation
April 30, 2025

Podcasts
The Lead Episode 100: A Discussion of Subcutaneous Implantable Defibrillators in Young Patients
April 18, 2025

Podcasts
The Lead Episode 99: A Discussion of Artificial Intelligence for Individualized Treatment of Persistent Atrial Fibrillation
April 15, 2025